Piperacillin 4gm & Tazobactam 500mg Injection

Piperacillin 4g + Tazobactam 500mg Injection
High-Dose Protection Against Resistant Infections

Piperacillin 4g + Tazobactam 500mg Injection is a powerful, broad-spectrum combination antibiotic designed for the treatment of severe, life-threatening infections, especially in intensive care and hospital settings. This formulation combines a high dose of Piperacillin, a potent antipseudomonal penicillin, with Tazobactam, a β-lactamase inhibitor, for enhanced activity against resistant bacterial strains.

Key Benefits:

• Maximum Strength Coverage:
  Ideal for treating serious infections caused by Gram-positive, Gram-negative, and anaerobic organisms, including Pseudomonas aeruginosa.

• Enhanced Resistance Protection:
  Tazobactam inhibits β-lactamase enzymes, preserving Piperacillin’s potency against resistant pathogens like ESBL-producing bacteria.

• Critical Care Ready:
  Preferred in ICUs, emergency departments, and surgical wards for high-risk infections.

• Rapid IV Administration:
  Achieves fast therapeutic levels in blood and tissues, ensuring quick clinical response.

Indications:

• Hospital-acquired pneumonia (HAP/VAP)

• Severe intra-abdominal infections

• Complicated urinary tract infections

• Septicemia and bloodstream infections

• Postoperative and gynecological infections

• Febrile neutropenia (in combination)

Dosage & Administration:
Administered intravenously. Standard adult dose: 4.5 g every 6–8 hours, or as directed by the physician. Adjust dose in renal impairment.

Important Safety Information:
Use with caution in patients with known hypersensitivity to penicillins. Monitor renal function, liver enzymes, and electrolyte balance during prolonged therapy. Common side effects may include nausea, diarrhea, rash, and infusion-site reactions.